Trials / Completed
CompletedNCT00363194
A Two-way Crossover Study Of The Effect Of Food On The Pharmacokinetics Of Pazopanib In Cancer Patients
An Open-Label, Two-Period, Randomized, Crossover Study to Evaluate the Effect of Food on the Pharmacokinetics of Single Doses of Pazopanib in Cancer Patients
- Status
- Completed
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 28 (actual)
- Sponsor
- GlaxoSmithKline · Industry
- Sex
- All
- Age
- 21 Years
- Healthy volunteers
- Not accepted
Summary
This is two-part study (Part I/Part II). Part I is designed to determine the effect of a low and high fat meal on the pharmacokinetics of single dose pazopanib (GW572016). Part II is designed to allow patients continued access to study drug in a multiple dosing regimen. Patients who are receiving clinical benefit on that regimen will go into the long term rollover study VEG105430 provided they are stable for 8 weeks.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Pazopanib (GW786034) | Pazopanib (GW786034) |
Timeline
- Start date
- 2006-09-21
- Primary completion
- 2009-06-19
- Completion
- 2009-06-19
- First posted
- 2006-08-15
- Last updated
- 2017-11-17
Locations
2 sites across 1 country: United States
Source: ClinicalTrials.gov record NCT00363194. Inclusion in this directory is not an endorsement.