Trials / Completed
CompletedNCT00356772
Azithromycin Level in Tears and in Conjunctiva in 36 Healthy Volunteers
Comparison of Azithromycin Level in Tears and in Conjunctiva After Repeated Instillations of T1225 1.5% Eye Drops or After a Single Per Os Administration of Zithromax® (Azithromycin 1g), in 36 Healthy Volunteers
- Status
- Completed
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- —
- Sponsor
- Laboratoires Thea · Industry
- Sex
- All
- Age
- 18 Years – 45 Years
- Healthy volunteers
- Accepted
Summary
To evaluate azithromycin ocular conjunctiva concentrations 7 and 14 days after treatment initiation. To assess ocular and systemic tolerance/safety and azithromycin tear concentrations on Day 7
Detailed description
The aim of the present study was to compare azithromycin tear and conjunctival ocular concentrations after one instillation of T1225 1.5% eye drops, twice a day during one day versus one instillation of T1225 1.5% eye drops, twice a day during 3 days versus an oral single dose of 1g azithromycin.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Azithromycin |
Timeline
- Start date
- 2003-02-01
- Completion
- 2003-03-01
- First posted
- 2006-07-26
- Last updated
- 2006-07-26
Source: ClinicalTrials.gov record NCT00356772. Inclusion in this directory is not an endorsement.