NCT00355966

Comparison of Misoprostol and PGE2 Gel for Induction of Labour in Women With Premature Rupture of Membranes at Term

Comparison of Misorostol & PGE2 Gel for Immediate Induction of Labour for Premature Ropture of Membranes at Term

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 212 (actual)
• Sponsor: Nilratan Sircar Medical College · Other Government
• Sex: Female
• Age: —
• Healthy volunteers: Not accepted

Summary

Induction of labour with vaginal misoprostol, in women with premature rupture of membranes at term, results in significant shortening of induction to delivery time in comparison to vaginal PGE2 gel induction.

Conditions

• Premature Rupture of Membranes at Term

Interventions

Type	Name	Description
DRUG	Misoprostol	In one group of women immediate induction of labour will be done by intravaginal misoprostol 25 microgram 4 hourly , a maximum of 5 doses .
DRUG	PGE2 gel	In other group immediate induction of labour will be done by intravaginal application of PGE2 gel 0.5 mg at an interval of 6 hours , a maximum of 2 doses.

Timeline

• Start date: 2006-08-01
• Primary completion: 2008-09-01
• Completion: 2008-09-01
• First posted: 2006-07-25
• Last updated: 2010-03-25

Locations

1 site across 1 country: India