NCT00352807

Absorption of Brimonidine Ophthalmic Solution in the Aqueous Humor of Cataract Patients

Absorption of Brimonidine Ophthalmic Solution in the Aqueous Humor of Cataract Patients.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 22 (planned)
• Sponsor: Indiana University School of Medicine · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to obtain and assay human aqueous samples following pre-operative dosing with 0.1% Brimonidine Purite™ (pH 7.8) or with 0.15% Brimonidine Purite® (pH 7.2) from patients undergoing routine cataract surgery in order to evaluate the aqueous concentration of the two formulations.Study hypothesis: The aqueous humor concentration 45 minutes following dosing of 0.1% Brimonidine Purite™ (pH 7.8) is comparable with 0.15% Brimonidine Purite® (pH 7.2)

Detailed description

The purpose of this study is to obtain and assay human aqueous samples following pre-operative dosing with 0.1% Brimonidine Purite™ (pH 7.8) or with 0.15% Brimonidine Purite® (pH 7.2) from patients undergoing routine cataract surgery in order to evaluate the aqueous concentration of the two formulations.

Conditions

• Cataract

Interventions

Type	Name	Description
DRUG	Brimonidine Purite

Timeline

• Start date: 2005-02-01
• Completion: 2005-12-01
• First posted: 2006-07-17
• Last updated: 2007-10-17

Locations

4 sites across 1 country: United States