NCT00345228

Myopic Macular Haemorrhages

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 30 (planned)
• Sponsor: Singapore National Eye Centre · Other Government
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

1. To identify the underlying causes of macular haemorrhages in patients with high myopia 2. In the eyes found to have macular haemorrhages secondary to choroidal neovascularisation, we hope to identify the risk factors for the development of choroidal neovascularisation in high myopia 3. To study the functional outcome of these eyes as assessed by visual acuity 4. To study the morphological outcome of these eyes by clinical assessment (and fundal photography) and fluorescein angiography

Detailed description

Primary Aims * To identify the underlying aetiologies of macular haemorrhages in myopic eyes * To study the functional and morphological outcome of these eyes with macular haemorrhages 6 months later Secondary Aims * To study the subgroup of eyes with myopic choroidal neovascularisation (CNV), in particular the risk factors for CNV in myopes * To study the subgroup of eyes with macular haemorrhages in the absence of CNV Plan of investigation: 1. Patient with myopia (\>-6.00DS) presents with loss of central vision 2. Examination reveals a macular haemorrhage 3. Investigations * Refraction * Axial length\* * Fundus fluorescein angiography * Indocyanine green angiography\* 4. Determine if a myopic CNV is present or absent 5. Management of patient: Treatment vs No treatment * Treatment being 1. Conventional laser 2. PDT 6. Review at 6 months * BCVA * Clinical appearance (fundal photo) * FFA 7. Review at 12 months * BCVA * Clinical appearance

Conditions

• Myopic Macular Haemorrhages

Timeline

• Start date: 2004-06-01
• Completion: 2006-12-01
• First posted: 2006-06-27
• Last updated: 2006-06-27

Locations

1 site across 1 country: Singapore