Trials / Completed
CompletedNCT00345124
The Effect of High and Low Sodium Intake on Urinary Aquaporin-2 in Essential Hypertension
The Effect of High and Low Sodium Intake on Urinary Aquaporin-2 in Essential Hypertension, During Basal Conditions and After Hypertonic Saline Infusion.
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 50 (actual)
- Sponsor
- Regional Hospital Holstebro · Academic / Other
- Sex
- All
- Age
- 18 Years – 65 Years
- Healthy volunteers
- Accepted
Summary
The aim of the study is to test the following hypotheses: * that the function and/or regulation of AQP2 and/or ENaC in the principal cells is abnormal in essential hypertension. * if an abnormal function of the principal cells is present in essential hypertension, this will become more pronounced at high and low sodium intake.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BEHAVIORAL | high sodium diet | 250-350 mmol |
| BEHAVIORAL | Low Sodium Diet | 25-35 mmol |
Timeline
- Start date
- 2006-05-01
- Primary completion
- 2009-05-01
- Completion
- 2009-08-01
- First posted
- 2006-06-27
- Last updated
- 2011-06-28
Locations
1 site across 1 country: Denmark
Source: ClinicalTrials.gov record NCT00345124. Inclusion in this directory is not an endorsement.