Clinical Trials Directory

Trials / Completed

CompletedNCT00334945

Evaluate the Effect of Growth Hormone (GH) Treatment on Fibroblast Growth Factor 23, a Known Phosphaturic Agent

Evaluate the Effect of Growth Hormone (GH) Treatment on Fibroblast Growth Factor 23 (a Known Phosphaturic Agent)

Status
Completed
Phase
Study type
Observational
Enrollment
35 (actual)
Sponsor
University of Alabama at Birmingham · Academic / Other
Sex
All
Age
3 Years – 14 Years
Healthy volunteers
Accepted

Summary

The purpose of this study is to evaluate the effect of growth hormone treatment on phosphorus levels in the body. Phosphorus is an important mineral for bone growth. It is well known that growth hormone treatment improves bone density and bone mineral content. The amount of phosphorus is maintained by the kidneys. Fibroblast Growth Factor 23 has recently been recognized to help kidneys control phosphate levels.

Detailed description

This study will compare Fibroblast Growth Factor 23 levels in children with and without growth hormone deficiency. Children with growth hormone deficiency will have levels taken before starting growth hormone replacement and after it has been initiated.

Conditions

Timeline

Start date
2006-04-01
Primary completion
2010-06-01
Completion
2011-08-01
First posted
2006-06-08
Last updated
2011-11-16

Source: ClinicalTrials.gov record NCT00334945. Inclusion in this directory is not an endorsement.