Clinical Trials Directory

Trials / Terminated

TerminatedNCT00334646

Cyclophosphamide Drug Interaction Study In Cancer Patients

An Open Label, Repeat Dose, Randomized, Two Period Crossover Study to Investigate the Potential Pharmacokinetic Interactions Between Oral GW679769 and Intravenous Cyclophosphamide in Cancer Patients

Status
Terminated
Phase
Phase 1
Study type
Interventional
Enrollment
25 (actual)
Sponsor
GlaxoSmithKline · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This study is designed to evaluate the potential pharmacokinetic interaction between oral GW679769 and IV (intravenous) cyclophosphamide when administered to cancer patients.

Conditions

Interventions

TypeNameDescription
DRUGOral GW679769150mg oral, once daily on days 1-3
DRUGIV Cyclophosphamide 500-700mg/m2IV Cyclophosphamide 500-700mg/m2 on day 1 of each cycle

Timeline

Start date
2005-08-10
Primary completion
2009-10-14
Completion
2009-10-14
First posted
2006-06-08
Last updated
2017-11-17

Locations

5 sites across 3 countries: United States, New Zealand, Sweden

Source: ClinicalTrials.gov record NCT00334646. Inclusion in this directory is not an endorsement.