NCT00323778

Prospective Assessment of the Efficacy of Hyaluronate Knee Injections in Patients With Osteoarthritis

Prospective Assessment of the Efficacy of Intra-Articular Hyaluronate to Affect Extracellular Matrix Changes in Patients With Osteoarthritis

• Status: Terminated
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Hospital for Special Surgery, New York · Academic / Other
• Sex: All
• Age: 45 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

This study looks at the effect of an injectable medication called Hyalgan on the cartilage of the knee in people who have osteoarthritis ("wear and tear arthritis") of the knee. Hyalgan is a medication which is injected into the knee, and is FDA approved to treat knee arthritis. We will be using magnetic resonance imaging (MRI) and x-rays to look at knee cartilage to see how it responds over the course of a year to the injections. A comparison to patients taking oral pain medication will be made.

Conditions

• Knee Osteoarthritis

Interventions

Type	Name	Description
DRUG	Hyalgan

Timeline

• Start date: 2006-05-01
• Primary completion: 2007-09-01
• First posted: 2006-05-10
• Last updated: 2008-02-06

Locations

1 site across 1 country: United States