Clinical Trials Directory

Trials / Completed

CompletedNCT00322374

Phase I Combination w/ Epirubicin

A Phase I Study of Ixabepilone in Combination With Epirubicin in Patients With Metastatic Breast Cancer

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
42 (actual)
Sponsor
R-Pharm · Industry
Sex
Female
Age
18 Years
Healthy volunteers
Not accepted

Summary

Tumor response information was obtained for all participants who received at least 2 cycles of study drug, underwent requisite baseline and on-treatment disease assessments and had at least one post-treatment assessment. Tumor response assessment in evaluable participants was done according to the Response Evaluation Criteria in Solid Tumors (RECIST) criteria.

Conditions

Interventions

TypeNameDescription
DRUGIxabepiloneInfusion, intravenous (IV), Cycle = 21 days. Dose escalation study.
DRUGEpirubicinInfusion, intravenous (IV): 75 mg/m\^2. Cycle = 21 days, up to 10 cycles or cumulative dose of 800 mg/m².

Timeline

Start date
2006-08-01
Primary completion
2009-02-01
Completion
2009-02-01
First posted
2006-05-05
Last updated
2016-03-10
Results posted
2010-08-10

Locations

2 sites across 2 countries: France, Italy

Source: ClinicalTrials.gov record NCT00322374. Inclusion in this directory is not an endorsement.