Clinical Trials Directory

Trials / Completed

CompletedNCT00321997

A Clinical Trial to Explore Safety and Efficacy of Different Doses of Pegaptanib Sodium, Compared to Sham, in Patients With Wet AMD.

A PHASE II/III RANDOMIZED, DOUBLE-MASKED, CONTROLLED, DOSE-RANGING, MULTI-CENTER COMPARATIVE TRIAL, IN PARALLEL GROUPS, TO ESTABLISH THE SAFETY AND EFFICACY OF INTRAVITREAL INJECTIONS OF EYE001 (ANTI-VEGF PEGYLATED APTAMER) GIVEN EVERY 6 WEEKS FOR 54 WEEKS, IN PATIENTS WITH EXUDATIVE AGE-RELATED MACULAR DEGENERATION (AMD)

Status
Completed
Phase
Phase 2 / Phase 3
Study type
Interventional
Enrollment
540 (planned)
Sponsor
Eyetech Pharmaceuticals · Industry
Sex
All
Age
50 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to compare the ability of different doses of pegaptanib sodium to safely and effectively minimize fluid leakage within the eye, thereby stabilizing or impriving vision in patients with wet AMD when compared to placebo injections.

Conditions

Interventions

TypeNameDescription
DRUGPegaptanib sodium

Timeline

Start date
2001-05-01
Completion
2007-10-01
First posted
2006-05-04
Last updated
2006-05-04

Source: ClinicalTrials.gov record NCT00321997. Inclusion in this directory is not an endorsement.