Clinical Trials Directory

Trials / Completed

CompletedNCT00321321

The Beta Cell Responsiveness to Glucose-dependent Insulinotropic Polypeptide (GIP) With and Without Sulfonylurea in Patients With Type 2 Diabetes

Phase 2 Study of The Beta Cell Responsiveness to GIP With and Without Sulfonylurea in Patients With Type 2 Diabetes

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
12 (actual)
Sponsor
University Hospital, Gentofte, Copenhagen · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The investigators hypothesize that the impaired insulinotropic effect of the incretin hormone GIP may be due to inadequate sensitization and ATP induced closure of beta cell K-ATP channels. By closing the channels through the use of sulfonylurea (SU) we hope to restore the insulinotropic effect of GIP.

Conditions

Interventions

TypeNameDescription
DRUGSulfonylurea

Timeline

Start date
2006-05-01
Primary completion
2007-03-01
Completion
2007-04-01
First posted
2006-05-03
Last updated
2015-07-16
Results posted
2008-10-02

Locations

1 site across 1 country: Denmark

Source: ClinicalTrials.gov record NCT00321321. Inclusion in this directory is not an endorsement.