Clinical Trials Directory

Trials / Completed

CompletedNCT00319592

A Safety and Efficacy Study of Two Japanese Encephalitis Vaccines ChimeriVaxTM-JE and JE-VAX

Randomized, Double-blind, Phase II Study of the Safety, Tolerability and Immunogenicity Following Administration of Live Attenuated JE Vaccine (ChimeriVax™ JE) Compared With Mouse Brain-derived Inactivated JE Vaccine (JE VAX®).

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
60 (actual)
Sponsor
Sanofi · Industry
Sex
All
Age
18 Years – 48 Years
Healthy volunteers
Accepted

Summary

The purpose of this study is to determine non-inferiority in seroconversion and to compare the safety and tolerability between ChimeriVax™-JE and JE-VAX® to the respective homologous virus strain and several wild types strains after completion of vaccination course.

Conditions

Interventions

TypeNameDescription
BIOLOGICALChimeriVax™-JE vaccine0.5 mL, subcutaneously
BIOLOGICALJE-VAX® vaccine1.0 mL, subcutaneously

Timeline

Start date
2005-05-01
Primary completion
2006-09-01
Completion
2006-09-01
First posted
2006-04-27
Last updated
2012-08-20
Results posted
2012-08-16

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT00319592. Inclusion in this directory is not an endorsement.