NCT00318227

Randomized Trial of a Liberal Versus a Restrictive Transfusion Strategy in Elderly Cardiac Surgery Patients

Evaluation of a Liberal Versus Restrictive Blood Transfusion Strategy in Elderly Patients Following Coronary Bypass or Aortic Valve Surgery

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 73 (actual)
• Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · Academic / Other
• Sex: All
• Age: 70 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether a less restrictive strategy of red blood cell transfusion in elderly patients following coronary bypass surgery results in enhanced postoperative recovery as determined by quality of life assessment, exercise tolerance and clinical outcomes. Two postoperative transfusion strategies: 1. Liberal - transfused when Hgb is \<100g/L 2. Restrictive - transfused when Hgb is \<70g/L

Conditions

• Anemia
• Coronary Artery Bypass Surgery

Interventions

Type	Name	Description
PROCEDURE	Blood Transfusion	Blood transfusion will be administered when the transfusion trigger is met.

Timeline

• Start date: 2004-06-21
• Primary completion: 2009-04-21
• Completion: 2010-02-23
• First posted: 2006-04-26
• Last updated: 2017-08-28

Locations

1 site across 1 country: Canada