Clinical Trials Directory

Trials / Completed

CompletedNCT00314561

The Effect of Pioglitazone and Rosiglitazone on Atherosclerotic and Inflammatory Markers in Patients With Metabolic Syndrome

The Effect of Pioglitazone and Rosiglitazone on Atherosclerotic and Inflammatory Markers in Patients With Metabolic Syndrome: A Prospective, Randomized, Open-label, Crossover Trial

Status
Completed
Phase
Phase 4
Study type
Interventional
Enrollment
40 (planned)
Sponsor
Korea University Anam Hospital · Academic / Other
Sex
All
Age
18 Years – 70 Years
Healthy volunteers
Not accepted

Summary

Pioglitazone and rosiglitazone are used in the treatment of diabetic patients. Thiazolidinediones increase insulin sensitivity and show favorable effect blood glucose levels and lipid profiles. The effect of these two different thiazolidinediones on atherosclerotic and inflammatory markers has not been compared in prospective manner. The purpose of this prospective, randomized, open-label, crossover trial is to compare the effect of pioglitazone and rosiglitazone on atherosclerotic and inflammatory markers in patients with metabolic syndrome.

Conditions

Interventions

TypeNameDescription
DRUGPioglitazone, Rosiglitazone

Timeline

Start date
2006-05-01
Completion
2006-12-01
First posted
2006-04-14
Last updated
2011-07-01

Locations

1 site across 1 country: South Korea

Source: ClinicalTrials.gov record NCT00314561. Inclusion in this directory is not an endorsement.