NCT00312923

Preliminary Study of Safety and Efficacy of Policosanol

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 54 (actual)
• Sponsor: Rush University Medical Center · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

Lay Language Summary: High cholesterol levels are common in persons with HIV infection. However, conventional cholesterol-lowering medications may have harmful side effects when given to HIV-infected persons. Therefore, we plan to evaluate the safety and effectiveness of policosanol, a dietary supplement derived from sugar cane that has cholesterol-lowering properties, to lower cholesterol levels in persons with HIV infection. We hypothesize that policosanol will lower levels of LDL cholesterol ("bad" cholesterol) and raise levels of HDL cholesterol ("good" cholesterol).

Detailed description

As per Brief Summary

Conditions

• Dyslipidemia
• HIV Infections

Interventions

Type	Name	Description
DRUG	Policosanol	20 mg of policosanol in capsular form daily
DIETARY_SUPPLEMENT	Placebo	Two capsules of 10 mg of microcrystalline cellulose daily

Timeline

• Start date: 2005-09-01
• Primary completion: 2009-07-01
• Completion: 2009-09-01
• First posted: 2006-04-11
• Last updated: 2013-07-26
• Results posted: 2013-07-15

Locations

1 site across 1 country: United States