Clinical Trials Directory

Trials / Completed

CompletedNCT00312858

Concomitant Use of Hepatitis A Vaccine With Measles, Mumps, Rubella and Varicella Vaccine and Pneumococcal 7-Valent Conjugate Vaccine in Healthy 12-Month-Old Children (V251-067)

An Open, Randomized, Multicenter Study of the Safety, Tolerability, & Immunogenicity of VAQTA™ Given Concomitantly With PROQUAD™ and PREVNAR™ in Healthy Children 12 Months of Age

Status
Completed
Phase
Phase 4
Study type
Interventional
Enrollment
653 (actual)
Sponsor
Merck Sharp & Dohme LLC · Industry
Sex
All
Age
12 Months – 15 Months
Healthy volunteers
Accepted

Summary

Hepatitis A vaccine will be given either alone or together with measles, mumps, rubella, and varicella vaccine and pneumococcal 7-valent conjugate vaccine at the first dose and together with measles, mumps, rubella, and varicella \[Oka/Merck\] virus vaccine at the second dose. Immunogenicity and safety data will be collected after each dose of vaccine.

Detailed description

Vaccines: V251, Hepatitis A Vaccine, Inactivated (VAQTA™) administered with Measles, Mumps, Rubella and Varicella Vaccine (ProQuad™) and Pneumococcal 7-Valent Conjugate Vaccine (Prevnar™) will have a Duration of Treatment: 2 Doses, 6 months apart. Vaccine: Hepatitis A Vaccine, Inactivated (VAQTA™), administered alone will have a Duration of Treatment: 2 Doses, 6 months apart.

Conditions

Interventions

TypeNameDescription
BIOLOGICALComparator: VAQTA™ (Hepatitis A vaccine)VAQTA™ 0.5 mL injection
BIOLOGICALComparator: ProQuad™ (Measles, Mumps, Rubella and Varicella vaccine)ProQuad™ 0.5 mL injection
BIOLOGICALComparator: Prevnar™ (Pneumococcal 7-Valent Conjugate vaccine)Prevnar™ 0.5 mL injection

Timeline

Start date
2006-04-01
Primary completion
2008-03-01
Completion
2008-03-01
First posted
2006-04-11
Last updated
2017-04-13
Results posted
2009-08-03

Source: ClinicalTrials.gov record NCT00312858. Inclusion in this directory is not an endorsement.