NCT00311259

Melatonin Treatment and Inflammation, Oxidative Stress and Autonomic Function in Connection With Surgery

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 40 (planned)
• Sponsor: University Hospital, Gentofte, Copenhagen · Academic / Other
• Sex: Female
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to determine whether treatment with melatonin can reduce cell damage and inflammation in connection with laparoscopic gall bladder surgery.

Detailed description

Laparoscopic gall bladder surgery is connected with changes in the body resulting in cell damage and inflammation. Melatonin is a hormone produced in brain and regulate sleep rhythm, temperature, production of other hormones and function of organs. Furthermore melatonin can modify cell damage and inflammation. After surgery the production of melatonin is disturbed. The purpose of this study is therefore to determine whether treatment with melatonin can reduce cell damage and inflammation in connection with laparoscopic gall bladder surgery.

Conditions

• Oxidative Stress
• Inflammatory Stress
• Myocardial Ischaemia

Interventions

Type	Name	Description
DRUG	Melatonin (drug)
DRUG	Laktose

Timeline

• Start date: 2006-05-01
• Completion: 2006-11-01
• First posted: 2006-04-05
• Last updated: 2006-04-05

Locations

1 site across 1 country: Denmark