Clinical Trials Directory

Trials / Terminated

TerminatedNCT00309517

Randomized Study on Neoadjuvant Radio-Chemotherapy in Rectal Carcinoma Dukes B and C

A Prospectively Randomized Study on Neoadjuvant Radio-Chemotherapy in Patients With Operated Rectal Carcinoma Dukes B and C (pT2, pN1-3; pT3-4, pN0-3; M0.

Status
Terminated
Phase
Phase 3
Study type
Interventional
Enrollment
700 (planned)
Sponsor
Austrian Breast & Colorectal Cancer Study Group · Network
Sex
All
Age
18 Years – 80 Years
Healthy volunteers
Not accepted

Summary

This clinical investigation examined the influence of preoperative radiotherapy in combination with postoperative 5-fluorouracil + leucovorin chemotherapy vs. 5-fluorouracil + leucovorin + MAb 17-1A chemo-immunotherapy on patients' local recurrence rate and overall survival time following surgery for rectal carcinoma Dukes B or C (T2-4, N0-3, M0).

Conditions

Interventions

TypeNameDescription
DRUGFluourouracil
DRUGLeucovorin
DRUGMAb 17-1A

Timeline

Start date
1997-07-01
First posted
2006-04-03
Last updated
2006-04-03

Locations

8 sites across 1 country: Austria

Source: ClinicalTrials.gov record NCT00309517. Inclusion in this directory is not an endorsement.