Trials / Terminated
TerminatedNCT00304980
Comparative Evaluation of the Safety and the Efficacy of 2 Antimalarials Depending on HIV Status
Comparative Evaluation of the Safety and the Efficacy of Artemether + Lumefantrine (Coartem™) vs. Sulfadoxine + Pyrimethamine (SP) in Both HIV+ and HIV- Adults With Uncomplicated P. Falciparum Malaria in Zambia
- Status
- Terminated
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 3,000 (planned)
- Sponsor
- Institute of Tropical Medicine, Belgium · Academic / Other
- Sex
- All
- Age
- 15 Years – 45 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to determine the safety and efficacy of sulfadoxine-pyrimethamine (SP) versus artemether-lumefantrine (Coartem) when administered to HIV+ and HIV- patients with uncomplicated P. falciparum malaria. Patients will be randomised to one of the 2 treatment and followed up (until day 14 actively) for 45 days.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | ARTEMETHER + LUMEFANTRINE VS. SULFADOXINE + PYRIMETHAMINE |
Timeline
- Start date
- 2003-03-01
- Completion
- 2005-04-01
- First posted
- 2006-03-21
- Last updated
- 2010-09-14
Locations
1 site across 1 country: Zambia
Source: ClinicalTrials.gov record NCT00304980. Inclusion in this directory is not an endorsement.