NCT00300495

Study of Amiodarone Given Before Lung Surgery to Prevent Atrial Fibrillation After Lung Resection

Phase III Study of Preoperative Amiodarone for Prevention of Atrial Fibrillation After Lung Resection

• Status: Terminated
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 19 (actual)
• Sponsor: Beth Israel Deaconess Medical Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Atrial fibrillation is a very common complication of pulmonary resection. Patients who develop atrial fibrillation require additional treatment and are more likely to stay in the hospital for longer period of time increasing the costs associated with the operation. We propose a randomized controlled trial to see if oral amiodarone given for one week before surgery can prevent atrial fibrillation after pulmonary resection. We plan to evaluate the incidence of atrial fibrillation in patients who received preoperative amiodarone and compare them to the incidence of atrial fibrillation in patients who did not received preoperative amiodarone.

Detailed description

Atrial fibrillation is a very common complication of pulmonary resection. Patients who develop atrial fibrillation require additional treatment and are more likely to stay in the hospital for longer period of time increasing the costs associated with the operation. We propose a study to see if oral amiodarone given for one week before surgery can prevent atrial fibrillation after pulmonary resection. We plan to evaluate the incidence of atrial fibrillation in patients who received preoperative amiodarone and compare them to the incidence of atrial fibrillation in patients who did not received preoperative amiodarone.

Conditions

• Atrial Fibrillation
• Lung Cancer

Interventions

Type	Name	Description
DRUG	Amiodarone	Perioperative orally administered
OTHER	Control arm, standard care	Control

Timeline

• Start date: 2006-02-01
• Primary completion: 2009-10-13
• Completion: 2009-10-13
• First posted: 2006-03-09
• Last updated: 2017-04-28
• Results posted: 2017-04-28

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study