NCT00298051

Umbilical Cord Clamping and Infant Iron Status

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 476 (actual)
• Sponsor: University of California, Davis · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

The aim of the study was to determine whether delayed umbilical cord clamping, as compared to early umbilical cord clamping, improves infant iron status at 6 months of age.

Detailed description

In developing countries, up to 50% of children become anemic by 12 months of age. Risk factors for iron deficiency (ID) include low birth weight, maternal prenatal ID, and male sex. Iron deficiency anemia (IDA) during infancy and childhood is of particular concern because of the potentially detrimental effects on development, some of which may be irreversible even after treatment to correct the deficiency. Delayed umbilical cord clamping is an intervention that increases the infant's iron endowment at birth and has been shown to increase hemoglobin (Hgb) concentration at two months of age. We determined whether a two-minute delay in the clamping of the umbilical cord of normal-weight, full-term infants significantly affected infant iron and hematological status through 6 months of age. In addition, we determined whether the effect of delayed cord clamping was significantly enhanced in subgroups of infants at higher risk of developing iron deficiency.

Conditions

• Iron-deficiency Anemia

Interventions

Type	Name	Description
PROCEDURE	Delayed umbilical cord clamping

Timeline

• Start date: 2003-10-01
• Primary completion: 2005-02-01
• Completion: 2005-02-01
• First posted: 2006-03-01
• Last updated: 2017-05-30

Locations

1 site across 1 country: Mexico