NCT00294749

Short or Long Schemes of Antibiotic Prophylaxis for Prostate Biopsy

Comparison Between Short and Long Schemes of Antibiotic Prophylaxis for Transrectal Prostate Biopsy. A Multicentre Prospective Randomised Study

• Status: Terminated
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 300 (estimated)
• Sponsor: Poitiers University Hospital · Academic / Other
• Sex: Male
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether long antibiotic prophylactic is more effective than a short traitement in infective complications for prostate biopsy

Detailed description

Prophylactic antibiotic is used to minimize the infective complications risk following transrectal biopsy of the prostate. The majority of works points to the need of antibiotic prophylaxis previously to transrectal prostate biopsy. However, there is a lot of controversy and diversity of therapeutic schemes in the literature concerning the ideal drug to be used and the time employed for infectious prophylaxis. The objective of this randomised study was to assess 2 different schemes of antimicrobial prophylaxis, aiming to determine the difference in infective complications with a single dose of ciprofloxacin 2 hours before the procedure vs. ciprofloxacin for 3 days

Conditions

• Men Who Must Undergo a Prostate Biopsy Related to Prostate Cancer Suspicion.

Interventions

Type	Name	Description
DRUG	Ciprofloxacine

Timeline

• Start date: 2006-02-01
• Primary completion: 2007-12-01
• Completion: 2008-04-01
• First posted: 2006-02-22
• Last updated: 2009-01-27

Locations

1 site across 1 country: France