NCT00293631

Study of Lornoxicam or Ketorolac or Placebo for Post-Operative Pain After Bunionectomy

A Randomized, Parallel-Group, Double-Blind, Single-Dose Study Evaluating the Efficacy and Safety of Intravenous Lornoxicam (8 mg and 16 mg) Compared to Intravenous Placebo and Ketorolac 30 mg in Management of Acute Postoperative Pain Following Orthopedic Surgery (Bunionectomy).

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 100 (planned)
• Sponsor: POZEN · Industry
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: —

Summary

To determine whether a single dose of intravenous lornoxicam is superior to intravenous placebo for management of post-operative pain in patients who have surgical removal of a bunion on the lower extremity. One-fourth of patients in this study will receive a single dose of intravenous ketorolac for management of pain and one-fourth of patients in this study will receive a single dose of an intravenous placebo.

Conditions

• Bunionectomy
• Orthopedic Surgery

Interventions

Type	Name	Description
DRUG	Lornoxicam 8 mg
DRUG	Lornoxicam 16 mg
DRUG	Ketorolac 30 mg
DRUG	Placebo

Timeline

• Start date: 2005-11-01
• Primary completion: 2006-03-01
• Completion: 2006-03-01
• First posted: 2006-02-17
• Last updated: 2012-12-03

Locations

1 site across 1 country: United States