Clinical Trials Directory

Trials / Completed

CompletedNCT00292708

Trial of Antibiotic Prophylaxis in Elective Colorectal Surgery

Randomized Multicenter Trial of Antibiotic Prophylaxis in Elective Colorectal Surgery: Single-Dose Vs. Three Doses of Second-Generation Cephalosporin

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
500 (planned)
Sponsor
National Cancer Center, Japan · Other Government
Sex
All
Age
20 Years – 80 Years
Healthy volunteers
Not accepted

Summary

To determine the optimal prophylactic antibiotics administration method in elective colorectal surgery

Detailed description

Use of prophylactic antibiotics in elective colorectal surgery is essential. Although single-dose prophylactic antibiotics are recommended, the efficacy of single-dose cephalosporin without metronidazole and oral antibiotics is not fully proven. We conducted a multicenter randomized trial of single-dose vs. three doses of the second-generation cephalosporin, cefmetazole.

Conditions

Interventions

TypeNameDescription
DRUGCefmetazole (drug)

Timeline

Start date
2004-05-01
Completion
2005-07-01
First posted
2006-02-16
Last updated
2006-02-16

Locations

7 sites across 1 country: Japan

Source: ClinicalTrials.gov record NCT00292708. Inclusion in this directory is not an endorsement.