Clinical Trials Directory

Trials / Completed

CompletedNCT00291226

Glycine vs Placebo for the Schizophrenia Prodrome

Status
Completed
Phase
Phase 2 / Phase 3
Study type
Interventional
Enrollment
8 (actual)
Sponsor
Yale University · Academic / Other
Sex
All
Age
13 Years – 35 Years
Healthy volunteers
Not accepted

Summary

Glycine is a natural amino acid neurotransmitter that acts as a co-agonist at NMDA receptors in brain. We hypothesize that symptoms of the schizophrenia prodrome will improve with glycine to a greater degree than with placebo.

Detailed description

A pilot clinical trial comparing glycine to placebo in patients with the schizophrenia prodrome.

Conditions

Interventions

TypeNameDescription
DRUGGlycineGlycine 0.4 g/kg bid
DRUGPlaceboPlacebo

Timeline

Start date
2006-03-01
Primary completion
2009-07-01
Completion
2009-07-01
First posted
2006-02-13
Last updated
2020-04-02
Results posted
2016-12-29

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT00291226. Inclusion in this directory is not an endorsement.