Clinical Trials Directory

Trials / Completed

CompletedNCT00290394

Ambulatory Blood Pressure Reduction After Rosiglitazone Treatment In Normotensive Type 2 Diabetic Patients

Study of PPAR Gamma Agonist-Rosiglitazone in Normotensive Type 2 Diabetics With Ambulatory Blood Pressure Monitoring

Status
Completed
Phase
Phase 4
Study type
Interventional
Enrollment
25 (planned)
Sponsor
Baskent University · Academic / Other
Sex
All
Age
49 Years – 65 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study was to determine the effects of rosiglitazone in normotensive type 2 diabetic patients with regard to its blood-pressure-reducing effects.

Detailed description

The first study to evaluate the effects of troglitazone on blood pressure in humans was published recently, which demonstrated a 5/4 mm Hg reduction in ambulatory blood pressure in 18 nondiabetic obese subjects after 12 weeks' treatment. Another study in 18 hypertensive subjects with diabetes mellitus showed an 18/12 mm Hg decline in office blood pressure after 8 weeks of treatment.

Conditions

Interventions

TypeNameDescription
DRUGrosiglitazone(drug), blood pressure lowering effect

Timeline

Start date
2004-03-01
Completion
2004-08-01
First posted
2006-02-13
Last updated
2006-02-13

Locations

1 site across 1 country: Turkey (Türkiye)

Source: ClinicalTrials.gov record NCT00290394. Inclusion in this directory is not an endorsement.