Trials / Terminated
TerminatedNCT00286663
Autoimmune Hepatitis Study
Evaluation of the Cellular Immune Response in Patients With Anti-SLA/LP- or Anti-LKM-Positive Autoimmune Hepatitis
- Status
- Terminated
- Phase
- —
- Study type
- Observational
- Enrollment
- 100 (estimated)
- Sponsor
- University of Rochester · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
The purpose of the study is to determine the role special antibodies play in possibly identifying Autoimmune Hepatitis through the following: Identify the response of specific T cells to antibodies and Monitor the response of the cells that regulate the immune system
Detailed description
The object of this protocol is to characterize and monitor auto antigen-specific T cell responses in blood and liver biopsies of patients with anti-SLA/LP or anti-LKM-positive autoimmune hepatitis. The results will provide insight into the pathogenesis of autoimmune hepatitis and the monitoring of auto antigen-specific T cell reactivity in correlation to disease exacerbation and therapy.
Conditions
Timeline
- Start date
- 2006-01-01
- Completion
- 2008-06-01
- First posted
- 2006-02-03
- Last updated
- 2008-07-09
Source: ClinicalTrials.gov record NCT00286663. Inclusion in this directory is not an endorsement.