Clinical Trials Directory

Trials / Terminated

TerminatedNCT00283634

A Study of Tarceva for Use in Patients With Relapsed or Refractory Metastatic Non-Small Cell Lung Cancer

A Randomized, Non-comparative, Multicenter, Open-Label, Phase 2 Study of Tarceva™ (Erlotinib) Alone and of Tarceva Plus VELCADE* (Bortezomib) for Injection in Patients With Relapsed or Refractory, Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
Sponsor
Millennium Pharmaceuticals, Inc. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Tarceva, an orally available small molecule, has demonstrated potent activity in tumor models and humans. This randomized, open-label phase 2 study of Tarceva alone and of Tarceva plus VELCADE is designed primarily to determine the objective tumor response rates to these treatments in patients with Stage IIIB or Stage IV non-small cell lung cancer (NSCLC) that is refractory to or has relapsed after front-line chemotherapy.

Conditions

Interventions

TypeNameDescription
DRUGerlotinib and bortezomib

Timeline

Start date
2005-08-01
Primary completion
2007-07-01
Completion
2007-08-01
First posted
2006-01-30
Last updated
2011-02-17

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT00283634. Inclusion in this directory is not an endorsement.

A Study of Tarceva for Use in Patients With Relapsed or Refractory Metastatic Non-Small Cell Lung Cancer (NCT00283634) · Clinical Trials Directory