NCT00276484

To Evaluate Ezetimibe Plus Atorvastatin Versus Atorvastatin in Patients With High Cholesterol Not Controlled on Atorvastatin 40 mg (0653-090)

A Multicenter, Rand., Double-Blind, Titration Study to Evaluate & Compare the Efficacy & Safety of Ezetimibe Plus Atorvastatin Vs Atorvastatin in Hypercholesterolemic Pts. at High Risk for CHD Not Adequately Controlled on Atorvastatin 40 Mg

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 579 (actual)
• Sponsor: Organon and Co · Industry
• Sex: All
• Age: 18 Years – 79 Years
• Healthy volunteers: Not accepted

Summary

To Evaluate and Compare the Efficacy and Safety of Ezetimibe Plus Atorvastatin Versus Atorvastatin in Hypercholesterolemic Patients at High Risk for Coronary Heart Disease Not Adequately Controlled on Atorvastatin 40 mg.

Conditions

• Hypercholesterolemia

Interventions

Type	Name	Description
DRUG	atorvastatin	Atorvastatin 80 mg tablet by mouth, once a day for 6 weeks
DRUG	atorvastatin	Atorvastatin 40 mg by mouth, once a day for 6 weeks
DRUG	ezetimibe	Ezetimibe 10 mg tablets by mouth, once a day for 6 weeks.

Timeline

• Start date: 2006-02-01
• Primary completion: 2008-02-01
• Completion: 2008-03-01
• First posted: 2006-01-13
• Last updated: 2024-05-14
• Results posted: 2009-04-13