NCT00273000

The Importance of Glucagon-Like Peptide-2 (GLP-2)in Mesenteric Bloodflow in Humans

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (planned)
• Sponsor: Glostrup University Hospital, Copenhagen · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to study the effect of GLP-2 on mesenteric bloodflow in healthy adults by the use of ultrasound., it is the hypothesis that GLP-2 vil increase the bloodflow.

Detailed description

The investigation will include 10 testpersons. It will be a 2 fase study over 2 days. day 1: The testperson will meet fasting, and take in a standard liquid meal, after this the bloodflow in a mesenteric artery will be measured by use of ultrasonic technique. Bloodsamples will be taken regular in a total wolumne of 200 ml. day 2:The testperson will meet fasting, there wil be administered intraveneous GLP-2 in 3 increasing doses over 3 x 45 min.and one subcutaneous dose. During this the bloodflow in a mesenteric artery will be measured by use of ultrasonic technique. Bloodsamples will be taken regular in a total wolumne of 200 ml.

Conditions

• Healthy

Interventions

Type	Name	Description
DRUG	GLP-2

Timeline

• Start date: 2006-01-01
• First posted: 2006-01-09
• Last updated: 2006-09-11

Locations

1 site across 1 country: Denmark