NCT00272324

Aspirin/Folate Prevention of Large Bowel Polyps

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 1,121 (planned)
• Sponsor: Dartmouth-Hitchcock Medical Center · Academic / Other
• Sex: All
• Age: 21 Years – 80 Years
• Healthy volunteers: Accepted

Summary

This is a randomized controlled trial of aspirin and/or folate supplementation for the prevention of the recurrence of neoplastic polyps (adenomas) of the large bowel.

Detailed description

This is a randomized controlled trial of aspirin and/or folate supplementation for the prevention of the recurrence of neoplastic polyps (adenomas) of the large bowel among subjects with a recent history of these tumors. The study is a randomized, double-blind, placebo-controlled trial with a 2 x 3 factorial design.

Conditions

• Colorectal Cancer
• Polyps
• Adenomas

Interventions

Type	Name	Description
DRUG	Aspirin
DRUG	Folate

Timeline

• Start date: 1992-02-01
• Completion: 2007-01-01
• First posted: 2006-01-05
• Last updated: 2020-03-13

Locations

9 sites across 2 countries: United States, Canada