NCT00263731

Metabolomic Analysis of Lung Cancer

Preoperative Metabolomic Analysis of Primary Lung Cancer: A Translational Clinical Trial of the Brown Cancer Center

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 249 (actual)
• Sponsor: University of Louisville · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to learn more about the metabolic properties of lung cancer cells.

Detailed description

It has long been known that cancer cells absorb and break down substances in the body differently than healthy, non-cancer cells. This process of absorbing and breaking down substances is known as metabolism and is increased in cancer cells. Recent research suggests that this increased metabolic activity makes it easier for cancer cells to multiply. The objective of the study is to characterize the metabolism of glucose by lung tumors by serum metabolite analysis, using a variant of glucose (sugar) which makes up 1% of glucose in nature.

Conditions

• Carcinoma, Non-Small Cell Lung
• Carcinoma, Small Cell Lung

Interventions

Type	Name	Description
OTHER	13-C-glucose	10 grams of 13-C-glucose intravenously, as a 30-minute "piggyback" infusion, 2 to 6 hours prior to scheduled surgical resection of primary lung cancer.

Timeline

• Start date: 2005-12-01
• Primary completion: 2020-09-24
• Completion: 2020-09-24
• First posted: 2005-12-09
• Last updated: 2022-05-09

Locations

1 site across 1 country: United States