Trials / Unknown
UnknownNCT00262574
Effect of BNP (Brain Natriuretic Peptides) on Endothelial Dysfunction Induced by Coronary Angioplasty
Phase 4 Study of Patients Receiving BNP or NTG (IV) During Angioplasty, Re-examined 24 Hours Later Using the Flow-mediated Brachial Artery Dilation Study, and Blood Assays for Pro BNP and ET1
- Status
- Unknown
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 500 (estimated)
- Sponsor
- The Baruch Padeh Medical Center, Poriya · Other Government
- Sex
- All
- Age
- —
- Healthy volunteers
- Not accepted
Summary
Patients receiving BNP or nitroglycerin (IV) during the angioplasty procedure. 24 h after the procedure, vascular reactivity will be re-examined using the brachial artery flow-mediated dilatation study. Blood assays for ET-1, pro-BNP, and various inflammatory markers will be checked before and 24 h after the procedure. It is our hypothesis that endothelial function will be better in the BNP treated patients compared to the NTG treated patients
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Nesiritide, | PCI |
Timeline
- Start date
- 2005-07-01
- Primary completion
- 2012-04-01
- Completion
- 2013-06-01
- First posted
- 2005-12-07
- Last updated
- 2011-08-09
Locations
1 site across 1 country: Israel
Source: ClinicalTrials.gov record NCT00262574. Inclusion in this directory is not an endorsement.