NCT00260624

Escitalopram Treatment of Patients With Agitated Dementia

Escitalopram in the Treatment of Patients With Agitated Dementia

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: University of Rochester · Academic / Other
• Sex: All
• Age: 61 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine the safety and efficacy of escitalopram (Lexapro) using 10 or 20 mg daily in patients with Alzheimer's disease who are also experiencing agitation.

Detailed description

This study is designed for men and women over 60 who have an established diagnosis of mild to severe Alzheimer's disease and who also present behaviors of agitation such as restlessness, physical aggression, yelling and socially inappropriate interactions. While nonpharmacologic interventions are preferable, many times they are not effective alone. Each consented subject will be enrolled in a 12 week study with escitalopram, 10 or 20 mg per day. Each subject will be evaluated using rating scales designed for symptoms of Alzheimer's and agitated behavior. Each subject will also undergo physical and neurological examinations, laboratory tests and monitoring of side effects of escitalopram.

Conditions

• Alzheimer's Disease
• Psychomotor Agitation

Interventions

Type	Name	Description
DRUG	Escitalopram (Lexapro)

Timeline

• Start date: 2003-02-01
• Primary completion: 2006-12-01
• Completion: 2006-12-01
• First posted: 2005-12-01
• Last updated: 2012-02-24

Locations

3 sites across 1 country: United States