Clinical Trials Directory

Trials / Completed

CompletedNCT00259701

Microvascular Reactivity.

Transdermal Application of Acetylcholine and Nitroglycerin Without Iontophoresis.

Status
Completed
Phase
Study type
Observational
Enrollment
20 (planned)
Sponsor
Yale University · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Accepted

Summary

This study attempts to test capillary responses to various challenges without the need for iontophoresis (electrical current).

Detailed description

Studies of microvascular responsiveness often employ iontophoresis to fascilitate drug absorption. Iontophoresis is a confounding stimulus in such studies, and we are attempting to create tests of the microvasculature that do not require iontophoretic drug delivery.

Conditions

Interventions

TypeNameDescription
DEVICELaser Doppler Flowmetry with topical acetylcholine and nitroglycerin

Timeline

Start date
2005-06-01
Completion
2005-09-01
First posted
2005-11-29
Last updated
2006-10-06

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT00259701. Inclusion in this directory is not an endorsement.

Microvascular Reactivity. (NCT00259701) · Clinical Trials Directory