Clinical Trials Directory

Trials / Completed

CompletedNCT00258635

Investigation of Safety+Efficacy of Different Doses of RagweedMATAMPL;Assessment of Residual Allergenicity Using Skin Prick Test

A Double-Blind Phase IIb Study to Evaluate the Safety and Efficacy of Different Doses of Tyrosine Adsorbed Ragweed Allergoid With MPL® With a Single-Blind Portion to Evaluate the Residual Allergenicity in Skin Test in Patients Sensitized to Ragweed Pollen.

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
69 (actual)
Sponsor
Allergy Therapeutics · Industry
Sex
All
Age
18 Years – 50 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to assess the immunological differences between three RagweedMATAMPL treatment arms compared to placebo with respect to immunoglobulin levels. In addition, the study will assess the reduced allergenicity of modified Ragweed Pollen contained in RagweedMATAMPL compared to unmodified native allergen using skin prick testing.

Conditions

Interventions

TypeNameDescription
BIOLOGICALRagweedMATAMPL

Timeline

Start date
2005-11-01
Primary completion
2006-08-07
Completion
2006-08-07
First posted
2005-11-28
Last updated
2021-06-11

Locations

4 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT00258635. Inclusion in this directory is not an endorsement.