Trials / Completed
CompletedNCT00258115
The Study of Inflammation on Blood Glucose Levels in Obese People
The Study of Inhibition of Inflammation in the Dysmetabolic Syndrome of Obesity
- Status
- Completed
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 20 (actual)
- Sponsor
- Joslin Diabetes Center · Academic / Other
- Sex
- All
- Age
- 18 Years – 30 Years
- Healthy volunteers
- Accepted
Summary
Chronic subaccute inflammation may underlie the development of diabetes cardiovascular disease and other components of the metabolic syndrome. Rodent studies suggest diet induced obesity is associated with activation of the IKK/NF-kB pathway and this pathway can be inhibited by salicylates. This study seeks to determine the effect of salicylates in overweight persons.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | salsalate |
Timeline
- Start date
- 2003-12-01
- Primary completion
- 2007-10-01
- First posted
- 2005-11-24
- Last updated
- 2018-02-15
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00258115. Inclusion in this directory is not an endorsement.