Clinical Trials Directory

Trials / Completed

CompletedNCT00256711

Phase II Iressa Versus Vinorelbine (INVITE)

A Randomised, Open Label, Parallel Group, Multi-Centre, Phase II Study of Progression Free Survival Comparing ZD1839 (IRESSA™) (250 MG Tablet) Versus Vinorelbine (30 MG/M2 Infusion) in Chemonaive, Elderly Patients With Locally Advanced (Stage IIIB) or Metastatic (Stage IV) NSCLC

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
192 (planned)
Sponsor
AstraZeneca · Industry
Sex
All
Age
70 Years
Healthy volunteers
Not accepted

Summary

This is a randomized, open label, parallel group, multi-centre, phase II study of progression free survival, comparing oral ZD1839 (IRESSA™) (250 mg tablet once daily) to vinorelbine 30 mg/m2 infusion on days 1 and 8 of a 21-day cycle) in chemonaïve, elderly patients with locally advanced (stage IIIB) or metastatic (stage IV) non-small cell lung cancer.

Conditions

Interventions

TypeNameDescription
DRUGGefitinib
DRUGVinorelbine

Timeline

Start date
2004-07-01
Completion
2006-02-01
First posted
2005-11-22
Last updated
2009-04-23

Locations

55 sites across 10 countries: Australia, Brazil, Czechia, France, Germany, Italy, South Africa, South Korea, Taiwan, United Kingdom

Source: ClinicalTrials.gov record NCT00256711. Inclusion in this directory is not an endorsement.