Clinical Trials Directory

Trials / Terminated

TerminatedNCT00250861

Trial of Outpatient Immunotherapy With Rituximab and Aldesleukin (IL-2) vs. Rituximab Alone for Non-Hodgkin's Lymphoma

A Randomized Phase II Trial of Outpatient Immunotherapy With Rituximab and Aldesleukin (IL-2) vs. Rituximab Alone for CD20 Positive Aggressive Non-Hodgkin's Lymphoma Following High Dose Therapy With Autologous PBSC Rescue

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
110 (planned)
Sponsor
US Oncology Research · Industry
Sex
All
Age
18 Years
Healthy volunteers

Summary

The purpose of this research study is to find out if treatment with rituximab in combination with aldesleukin (compared to rituximab alone) decreases the risk of cancer returning, as well as determining what other effects (good and bad) this drug combination has on NHL. Rituximab and aldesleukin are not approved in combination by the Food and Drug Administration (FDA) for the treatment of non-Hodgkins lymphoma; however, Rituximab is approved for use by itself to treat NHL.

Conditions

Interventions

TypeNameDescription
DRUGRituximab
DRUGAldesleukin

Timeline

Start date
2005-10-01
Primary completion
2007-08-01
Completion
2007-08-01
First posted
2005-11-08
Last updated
2008-04-21

Locations

21 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT00250861. Inclusion in this directory is not an endorsement.