Clinical Trials Directory

Trials / Completed

CompletedNCT00246688

Efficacy and Safety Study of ZK219477 in Patients With Recurrent Ovarian Cancer

Randomized, Multicenter, Prospective Two-arm, Open-label Phase II Study to Investigate the Efficacy and Safety of Two ZK219477 i.v. Infusions (3-hour Infusion of 16mg/m2 Versus 0.5-hour Infusion of 16 mg/m2) in Patients With Recurrent Ovarian Cancer Progressing During, or Within 6 Months of the End of Platinum-based Chemotherapy

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
63 (actual)
Sponsor
Bayer · Industry
Sex
Female
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to determine if this epothilone leads to a response in patients with recurrent ovarian cancer that has progressed during, or in the last six months since a treatment of platinum-based chemotherapy. We also aim to look at the safety of the study drug and assess the impact of the infusion duration on tolerability.

Detailed description

The study has previously been posted by Schering AG, Germany. Schering AG, Germany has been renamed to Bayer Schering Pharma AG, Germany.Bayer Schering Pharma AG, Germany is the sponsor of the trial.

Conditions

Interventions

TypeNameDescription
DRUGSagopilone (BAY86-5302 , ZK219477)10.5 mg lyophilized sagopilone per vial

Timeline

Start date
2005-11-01
Primary completion
2007-06-01
Completion
2007-06-01
First posted
2005-10-31
Last updated
2015-12-31

Source: ClinicalTrials.gov record NCT00246688. Inclusion in this directory is not an endorsement.