Trials / Completed
CompletedNCT00244530
Prophylactic Effect of Nifedipine on Further Decline in Renal Function in Patients Undergoing Open-Heart Surgery
Postoperative Renal Function After Open-Heart Surgery in Patients With Impaired Renal Function Preoperatively. A Study of the Calcium Channel Blocker Nifedipine's Prophylactic Effect on Further Decline in Renal Function.
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 20 (planned)
- Sponsor
- University of Oslo School of Pharmacy · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
To compare renal function (51Cr-EDTA clearance) 48 hours post open-heart surgery (coronary bypass or valve surgery) in patients with impaired renal function after randomization to either nifedipine infusion at start of surgery and the following 24 hours or placebo (0.9% saline infusion). Study hypothesis is that nifedipine has a prophylactic effect on decline in renal function.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Nifedipine |
Timeline
- Start date
- 2001-06-01
- Completion
- 2005-10-01
- First posted
- 2005-10-26
- Last updated
- 2006-12-22
Locations
1 site across 1 country: Norway
Source: ClinicalTrials.gov record NCT00244530. Inclusion in this directory is not an endorsement.