NCT00241410

Safety, Immunological Effect and Efficacy of the Combined Application of MPL and Grass Pollen Allergen

Investigation of the Safety, Immunological Effect and Efficacy of the Combined Application of MPL and Grass Pollen Allergen

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 86 (actual)
• Sponsor: Allergy Therapeutics · Industry
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

Safety and tolerability of different dose combinations of MPL and grass pollen allergen and to identify the highest combinations of MPL and grass pollen allergen which is safe. Pharmacodynamics and efficacy of MPL and grass pollen allergen.

Detailed description

Objective of this trial is to demonstrate the safety and tolerability of different dose combinations of MPL and grass pollen allergen and to identify the highest combination of MPL and grass pollen allergen which is safe. Other objectives are to investigate the pharmacodynamics and efficacy of MPL and grass pollen allergen.

Conditions

• Type I Hypersensitivity

Interventions

Type	Name	Description
BIOLOGICAL	OralvacB2MPL	Comparison of different dosages of drug

Timeline

• Start date: 2005-12-01
• Primary completion: 2007-01-01
• Completion: 2007-01-01
• First posted: 2005-10-19
• Last updated: 2010-06-17

Locations

1 site across 1 country: Germany