NCT00235378

Genetic Study of Lupus Patients and Their Families

Gene Mapping in Women With SLE

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 2,356 (actual)
• Sponsor: Oklahoma Medical Research Foundation · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

The purpose of this study is to perform genetic testing in and to collect information from families affected by lupus in order to identify the genetic factors associated with systemic lupus erythematosus (SLE).

Detailed description

Little is known about the genetic factors that predispose people to developing SLE. Genes in patients with SLE may provide clues about SLE's pathogenesis. This study will compare genes from SLE patients, their unaffected family members, and control participants. Travel to the study site is not required. In this study, blood samples will be collected from people diagnosed with SLE, their unaffected family members, and condition-matched controls. Participants will be asked questions about their health and will provide a small blood sample. Participants will also be asked to provide written permission for release of medical information, so that their disease status can be verified through medical record review or through consultation with their doctors. Study personnel may contact participants in the future for follow-up questions and additional blood draws, if the participant agrees.

Conditions

• Systemic Lupus Erythematosus

Timeline

• Start date: 1996-07-01
• Primary completion: 2013-03-01
• Completion: 2013-03-01
• First posted: 2005-10-10
• Last updated: 2015-10-15

Locations

1 site across 1 country: United States