NCT00235183

Plasma Transfusion in Liver Transplantation

Plasma Transfusion in Liver Transplantation : a Randomized, Double Blind, Multicenter Trial of Methylene Blue, Solvent/Detergent and Quarantined Plasma.

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 300 (estimated)
• Sponsor: Etablissement Français du Sang · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The aim of the study is to compare the clinical efficacy of three types of plasma secured on the viral level either by quarantine or by chemical treatment in patients undergoing liver transplantation.

Detailed description

Three types of plasma are transfused in bleeding patients undergoing liver transplantation: * quarantined plasma, * methylene blue treated plasma, * solvent/detergent plasma. The main purpose is to show that the volume of methylene blue treated plasma consumed intraoperatively is equivalent to that of the 2 other types of plasma. In addition, the correction of coagulation abnormalities are studied.

Conditions

• Bleeding in Liver Transplantation

Interventions

Type	Name	Description
OTHER	plasma	transfusion of more than 15 mL/Kg of plasma

Timeline

• Start date: 2005-06-01
• Primary completion: 2009-12-01
• Completion: 2010-12-01
• First posted: 2005-10-10
• Last updated: 2014-02-17

Locations

1 site across 1 country: France