NCT00235079

Study of Colchicine to Treat and Prevent Recurrent Pericarditis After Failure of Conventional Treatment.

Treatment and Prevention of Pericarditis With Colchicine. A Multicenter Double Blind Randomized Trial. The CORP 2 Trial: COlchicine for Recurrent Pericarditis.

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 240 (actual)
• Sponsor: Azienda Sanitaria Locale 3, Torino · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of the study is to determine whether colchicine is safe and effective in treatment and prevention of recurrent pericarditis after failure of conventional treatment.

Detailed description

Colchicine is safe and effective in the management of recurrent pericarditis after failure of conventional treatment. Preliminary data (observational, non-randomized studies without a control group) have shown that the drug may be effective in treatment of the second and subsequent recurrence and the prevention of further recurrences.

Conditions

• Pericarditis
• Recurrence

Interventions

Type	Name	Description
DRUG	Colchicine	Colchicine 0.5mg BID (\>70Kg) or 0.5 once daily for 6 months
DRUG	Placebo	Placebo comparator

Timeline

• Start date: 2005-11-01
• Primary completion: 2011-12-01
• Completion: 2011-12-01
• First posted: 2005-10-10
• Last updated: 2013-08-07

Locations

4 sites across 1 country: Italy