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Trials / Completed

CompletedNCT00234923

Efficacy and Safety of Kaletra Monotheraphy Compared to Kaletra Based Triple Therapy to Treat HIV in Antiretroviral Naїve Patients

A Pilot, Open-Label, Randomized, Comparative Study of the Antiviral Efficacy of Lopinavir/Ritonavir Single-Drug Regimen Versus Lopinavir/Ritonavir in Combination With Lamivudine/Zidovudine in Antiretroviral Naïve Patients

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
138 (actual)
Sponsor
Abbott · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this pilot study is to obtain a preliminary assessment of the antiviral activity and tolerability of Kaletra single agent therapy as initial treatment for HIV infection, relative to a Kaletra three drug standard of care reference arm

Conditions

Interventions

TypeNameDescription
DRUGlopinavir/ritonavir400 mg lopinavir/ 100 mg ritonavir, BID
DRUGlamivudine/zidovudine300mg lamivudine/150mg zidovudine, BID

Timeline

Start date
2003-08-01
Primary completion
2007-02-01
First posted
2005-10-10
Last updated
2008-04-03

Source: ClinicalTrials.gov record NCT00234923. Inclusion in this directory is not an endorsement.

Efficacy and Safety of Kaletra Monotheraphy Compared to Kaletra Based Triple Therapy to Treat HIV in Antiretroviral Naїv (NCT00234923) · Clinical Trials Directory