Clinical Trials Directory

Trials / Terminated

TerminatedNCT00226785

Dexmedetomidine for Continuous Sedation

A Prospective, Multi-Centre, Randomised, Double-Blind Comparison of Intravenous Dexmedetomidine With Propofol/Midazolam for Continuous Sedation (24 Hours to 14 Days) of Ventilated Patients in Intensive Care Unit

Status
Terminated
Phase
Phase 3
Study type
Interventional
Enrollment
900 (planned)
Sponsor
Orion Corporation, Orion Pharma · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The study aims to demonstrate that dexmedetomidine is non-inferior to current best practice sedation with propofol/midazolam and daily sedation stops, in maintaining a target depth of sedation in long-stay intensive care unit (ICU) patients, and that dexmedetomidine, compared with current best practice, reduces the length of ICU stay.

Conditions

Interventions

TypeNameDescription
DRUGDexmedetomidine

Timeline

Start date
2005-10-01
Completion
2006-07-01
First posted
2005-09-27
Last updated
2006-11-14

Locations

4 sites across 2 countries: Finland, Switzerland

Source: ClinicalTrials.gov record NCT00226785. Inclusion in this directory is not an endorsement.

Dexmedetomidine for Continuous Sedation (NCT00226785) · Clinical Trials Directory