Clinical Trials Directory

Trials / Completed

CompletedNCT00225719

Effect of rHDL on Atherosclerosis - Safety and Efficacy: THE ERASE TRIAL

Regression of Coronary Atherosclerotic Lesions After rHDL Infusions in Acute Coronary Syndrome Patients as Assessed by Intravascular Ultrasound.

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
180 (estimated)
Sponsor
CSL Limited · Industry
Sex
All
Age
30 Years – 75 Years
Healthy volunteers
Not accepted

Summary

Currently available therapies to treat Acute Coronary Syndromes(ACS) have several limitations including; the relatively long treatment duration required before apparent significant benefit; the inability to achieve reversal of the atherosclerotic process; and poor patient compliance due to chronicity of therapy. This study will assess the effects of rHDL compared with placebo on indices of atherosclerosis progression and regression as assessed with intravascular ultrasound (IVUS) in patients after acute coronary syndromes (ACS).

Conditions

Interventions

TypeNameDescription
DRUGrHDL

Timeline

Start date
2005-07-01
First posted
2005-09-26
Last updated
2008-11-10

Locations

1 site across 1 country: Canada

Source: ClinicalTrials.gov record NCT00225719. Inclusion in this directory is not an endorsement.