NCT00225238

The Effects of Nexium on the Side Effects Associated With a Colonoscopy Prep

The Effect of Esomeprazole (Nexium) on the Incidence and Severity of Gastrointestinal Adverse Events Associated With a Colonoscopy Purgative

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 500 (actual)
• Sponsor: Thomas Jefferson University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to ascertain if the use of Nexium for 7 days prior to taking a colon prep for a colonoscopy will decrease the side effects that are associated with the colon preparation

Detailed description

The high incidence for colon cancer make it an ideal target for screening. In the United Staes there are approximately 100,00 new cases of colon cancer yearly. Typically the progression from polyps to cancer requires years. This permits a screening procedure to identify polyps befoere they are cancerous. Colon cleansing is required prior to colonoscopy. The gastrointestinal syptoms associted with colonic preps are common and oftn assoicated wwith upper gastrointestinal disorders including GERD, non-ulcer syspepsia, and gastric dysmotoility such as gastropareesis.

Conditions

• Nausea
• Vomiting
• Abdominal Pain

Interventions

Type	Name	Description
DRUG	esomeprazole (PPI)

Timeline

• Start date: 2003-12-01
• Primary completion: 2007-10-01
• Completion: 2007-10-01
• First posted: 2005-09-23
• Last updated: 2013-06-05

Locations

1 site across 1 country: United States